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In Genome Biology this week, scientists led by those at EMBL in Heidelberg used what they call a "trans-regulation screen" to study the regulation of Ath5, the central node in the gene regulatory network controlling retinal ganglion cell differentiation in vertebrates. They were able to identify potential Ath5 regulators that they then validated in vivo by functional assays in medakafish embryos.

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Bloomberg reports AstraZeneca may conduct another study of its candidate SARS-CoV-2 vaccine after dosing error.

Moderna is applying for an Emergency Use Authorization for its coronavirus vaccine, according to the New York Times.

The National Health Service is to conduct a trial of Grail's blood-based screening test for cancer.

In PLOS this week: somatic mutation patterns of glioblastomas among Lebanese patients, phenome-wide study using UK Biobank data, and more.