In Genome Biology this week, scientists led by those at EMBL in Heidelberg used what they call a "trans-regulation screen" to study the regulation of Ath5, the central node in the gene regulatory network controlling retinal ganglion cell differentiation in vertebrates. They were able to identify potential Ath5 regulators that they then validated in vivo by functional assays in medakafish embryos.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Vivek Murthy is no longer the surgeon general of the US, the Associated Press reports.

People around the globe took to the streets to support science — some with signs.

Parents who learn of their increased genetic risk of disease also contend with telling their children about theirs, the New York Times writes.

In PLOS this week: loci linked to body mass index measurements, long non-coding RNA expression and urothelial carcinoma prognosis, and more.