This Week in Cell

In a Cell paper published online in advance this week, an international team led by investigators at Children's Hospital Boston shows that "the RNA exosome targets the AID [activation-induced cytidine deaminase ] … to both strands of transcribed duplex DNA substrates." More specifically, the authors write, the RNA exosome "accumulates on IgH switch regions in an AID-dependent fashion," a process that is "required for optimal" class switch recombination.

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Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.

Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.

Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.

In PLOS this week: mechanisms for genes implicated in coronary artery disease, rumen microbes and host genetics influence cow methane production, and more.