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In Cell this week, a team led by researchers at the University of Wisconsin-Madison shows that the mitochondrial deacetylase "Sirt3 is an essential player in enhancing the mitochondrial glutathione antioxidant defense system" during caloric restriction in mice, and that consequently, it "slows the progression of age-related hearing loss." The team found that, in wild-type mice, caloric restriction "reduces oxidative DNA damage in multiple tissues and prevents AHL," but it does not do so in

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Researchers are developing a breath test to determine how severe patients' methylmalonic acidemia disease is, FierceBiotech reports.

NPR reports that vaccine developers are working on SARS-CoV-2 vaccines that are easier to store or administer than the current crop.

Reuters reports that France is to recommend that people under 55 who received one dose of AstraZeneca's SARS-CoV-2 vaccine receive a different vaccine for their second dose.