This Week in Cell

In Cell Metabolism this week, Francis Collins and his colleagues at the National Human Genome Research Institute provide a "global snapshot of the human islet epigenome," with which they've elucidated insights into type 2 diabetes susceptibility loci. By performing a genome-wide analysis of sites hypersensitive to DNAse I, the NHGRI-led team found around 18,000 putative promoters, several hundred of which were previously "unannotated and islet-active," the authors write.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.