This Week in Cell

A University of California at San Francisco-led team presented CRISPR-based strategies to systematically repress and activate the transcription of endogenous human genes. As they report online in Cell, the researchers started by screening the activity of short guide RNAs (sgRNAs) tiling to sequences in and around transcription start sites for dozens of genes mediating ricin susceptibility in cells.

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Two researchers have found that behavioral genetic defenses in criminal cases don't tend to affect outcomes, according to Popular Science.

Researchers report that while host genetics influence the oral microbiome, they don't appear to affect cavity-causing microbes, the Economist says.

Pandas' gut microbiomes change as what they eat changes with the seasons, writes Discover's Inkfish blog.

In PLOS this week: comparative genomic study of malaria-linked macaque parasite, search for apple root reference genes, and more.