This Week in Cell | GenomeWeb

This Week in Cell

A University of California at San Francisco-led team presented CRISPR-based strategies to systematically repress and activate the transcription of endogenous human genes. As they report online in Cell, the researchers started by screening the activity of short guide RNAs (sgRNAs) tiling to sequences in and around transcription start sites for dozens of genes mediating ricin susceptibility in cells.

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Harold Varmus, a former NIH director, says that proposed reductions to the agency's budget are worrisome.

The Genome 10K project is to sequence about 10,000 vertebrate genomes, including ones of endangered species, Digital Trends reports.

The new Coalition to Save NIH Funding aims to educate lawmakers and the public on the significance of biomedical research.

In PLOS this week: analysis of viral sequences from human blood samples, gut microbiomes of heart failure patients, and more.