This Week in Cell

A University of California at San Francisco-led team presented CRISPR-based strategies to systematically repress and activate the transcription of endogenous human genes. As they report online in Cell, the researchers started by screening the activity of short guide RNAs (sgRNAs) tiling to sequences in and around transcription start sites for dozens of genes mediating ricin susceptibility in cells.

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A Columbia University-led team used emergency contact information from medical records to create family trees and estimate disease heritability.

Parabon NanoLabs is partnering with law enforcement to use genetic genealogy approaches to solve cold cases, Buzzfeed News reports.

In Science this week: ancient Southeast Asian genomes provide insight on human migration, and more.

NPR says a new report recommends that former research chimpanzees should be moved to retirement sanctuaries unless that move would shorten their lives.