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In Cell this week, researchers in Spain and Philadelphia used a GENCODE annotations of the human genome to characterize more than 1,000 long noncoding RNAs that are expressed in multiple cell lines, and found an enhancer-like function for a set of the long ncRNAs in human cell lines. "Depletion of a number of ncRNAs led to decreased expression of their neighboring protein-coding genes, including the master regulator of hematopoiesis, SCL (also called TAL1), Snai1 and Snai2," the authors write.

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