This Week in Cell

In a paper appearing in Cell, researchers from the University of Chicago report that Mendelian variants likely also contribute to the development of complex diseases. The team scoured the medical records of more than 110 million patients in the US and Denmark, it found that there are thousand of connections between Mendelian variants and complex diseases. Each disease, the team adds, appears to have a unique Mendelian disease allelic architecture that forms a type of code for that disease.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.