This Week in Cell

In a paper appearing in Cell, researchers from the University of Chicago report that Mendelian variants likely also contribute to the development of complex diseases. The team scoured the medical records of more than 110 million patients in the US and Denmark, it found that there are thousand of connections between Mendelian variants and complex diseases. Each disease, the team adds, appears to have a unique Mendelian disease allelic architecture that forms a type of code for that disease.

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