This Week in Cell | GenomeWeb

This Week in Cell

The Massachusetts Institute of Technology's Rudolf Jaenisch and colleagues report on a genome editing approach that takes advantage of a type II bacterial CRISPR/CAS system. By directing messenger RNA from the Cas9 gene to genomic sequences of interest with the help of single-guided RNAs, the researchers demonstrated that they could generate mice carrying fluorescent tags or conditional mutations at several genes in a single step.

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