This Week in Cell

The Massachusetts Institute of Technology's Rudolf Jaenisch and colleagues report on a genome editing approach that takes advantage of a type II bacterial CRISPR/CAS system. By directing messenger RNA from the Cas9 gene to genomic sequences of interest with the help of single-guided RNAs, the researchers demonstrated that they could generate mice carrying fluorescent tags or conditional mutations at several genes in a single step.

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In PNAS this week: epigenetic changes linked with high-altitude pulmonary edema, transcriptome profiling of maize leaf development, and more.

Stanford University researchers are studying top athletes to uncover genes linked to performance.

The UW's Wylie Burke and Dartmouth's Gilbert Welch argue that whole-genome testing may do more harm than good, and a related poll.

In PLOS this week: phylogenetic study of hepatitis E viruses in Swedish moose, recombination sites in the honeybee genome, and more.