This Week in Cell: Sep 8, 2010

Sep 08, 2010

In Cell this week, investigators at the Stowers Institute for Medical Research in Kansas City, Mo., show that "the ATAC acetyltransferase complex coordinates MAP kinases to regulate JNK target genes." Specifically, the team found that "ATAC subunits are required for c-Jun occupancy of these genes and for H4K16 acetylation at the Jra enhancer, promoter, and transcribed sequences." In addition, ATAC co-localizes with c-Jun, the team shows, and recruits the upstream kinases Misshpane,

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