This Week in Cell

The University of Massachusetts Medical School's Craig Mello and his colleagues report in Cell that they have uncovered a new type of piwi-interacting RNA in Caenorhabditis elegans. Using a new enzymatic method for 5' anchored RNA profiling called CapSeq, the researchers found a number of candidate transcription start sites for piRNA precursors. However, the researchers say that using that they could not identify the vast majority of piRNA loci.

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