This Week in Cell | GenomeWeb

This Week in Cell

An international team led by René Bernards, with The Netherlands Cancer Institute and Agendia, explores the genetics of cancer treatment susceptibility and resistance, focusing first on ALK and EGF receptor tyrosine kinase inhibitor therapies. Using an RNA interference screen in a non-small cell lung cancer line carrying an EML4-ALK translocation, the researchers determined that knocking down a gene called MED12 confers resistance to an ALK-inhibiting drug called crizotinib.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

Epigenetic Response

This Week in Science

This Week in PNAS

This Week in PNAS

This Week in PNAS

In Nature this week: SNP reference panel from the Haplotype Reference Consortium, and more.

Halloran Consulting's Laurie Halloran lists at Stat News the mistakes she sees startup companies make when pursuing a clinical trial.

MIT researchers are using bees to collect and visualize urban microbiome samples, Wired reports.

Reliance on Excel leads to errors in gene name lists, a new Genome Biology paper reports.