This Week in Cell

The skin cancer melanoma is characterized by a dip in 5-hydroxymethylation at cytosine nucleotides across the genome, according to a study in the September 14th issue of Cell. Researchers from the US, China, and Australia used several approaches to show that primary and metastatic melanoma samples have unusually low levels of 5-hmC methylation compared with normal melanocyte cells or benign skin growths.

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