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In Cell this week, investigators in France and the US show that "single-stranded DNA transposition is coupled to host replication." They describe a connection between the transposition of IS608 and ISDra2 — members of the same insertion sequence family — which they suggest "uses obligatory single-stranded DNA intermediates, and the host replication fork." Thus, the authors report, "replication direction through the IS plays a crucial role in excision," in that, replication activity

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A UK study on mixing SARS-CoV-2 vaccines is expanding to include vaccines developed by additional companies, according to the Guardian.

According to Science, the US National Academy of Sciences is poised to eject two members accused of sexual harassment.

In Nucleic Acids Research this week: machine learning approach to detect DNA-bound proteins, CRISPR-based method for activating specific gene targets, and more.

The FDA and CDC call for a pause in administering Johnson & Johnson's SARS-CoV-2 vaccine while reports of rare blood clots are looked into, reports the Wall Street Journal.