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In Cell this week, investigators in France and the US show that "single-stranded DNA transposition is coupled to host replication." They describe a connection between the transposition of IS608 and ISDra2 — members of the same insertion sequence family — which they suggest "uses obligatory single-stranded DNA intermediates, and the host replication fork." Thus, the authors report, "replication direction through the IS plays a crucial role in excision," in that, replication activity

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President-elect Joe Biden has nominated Eric Lander to serve as director of the Office of Science and Technology Policy, the Associated Press says.

Nature News writes that scientists are trying to figure out how to name the new strains of SARS-CoV-2 that are emerging.

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