This Week in Cell | GenomeWeb

This Week in Cell

In a paper published online in advance in Molecular Cell this week, researchers at the University of Zurich show that poly(ADP-ribose)-polymerase-1, or PARP1/ARTD1, "is implicated in the maintenance of silent rDNA chromatin during cell division." More specifically, the team shows that "PARP1 associates with TIP5 … via the noncoding pRNA and binds to silent rRNA genes after their replication in mid-late S phase," such that it represses rRNA transcription and plays a role in the formation of silent rDNA chromatin.

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The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.

The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.

Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.

In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.