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Rockefeller University's Ronen Sadeh and C. David Allis discuss in the current issue of Cell the relevance of recent studies that have mapped nucelosomes across the yeast and human genomes. Sadeh and Allis say that data from these studies suggest two models of nucleosome organization: "Chromatin remodelers position nucleosomes around transcriptional start sites in yeast, and a few locked nucleosomes may serve as barriers from which nucleosome arrays emanate in human genomes."

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The US Food and Drug Administration is to announce stricter standards for emergency authorizations of SARS-CoV-2 vaccines, reports the Washington Post.

The Associated Press reports Johnson & Johnson is starting a late-stage clinical trial of its candidate SARS-CoV-2 vaccine.

Bloomberg reports the budget of Operation Warp Speed is actually $18 billion, higher than the number typically cited.

In Genome Research this week: genomic analysis reveals role of super-spreaders in SARS-CoV-2, epigenetic drivers of cancer, and more.