This Week in Cell

New York University School of Medicine's Evgeny Nudler et al. link RNA polymerase backtracking to genome instability in E. coli in Cell this week. In its paper, the NYU team shows that "co-directional collisions between backtracked RNAP [RNA polymerase] and replisome lead to DSBs [double-strand breaks]" in the bacterium. It also shows that "active ribosomes preserve genome integrity" by preventing such backtracking.

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Researchers describe a way to share data while keeping it secure, Agence France Presse reports.

India's Council of Scientific and Industrial Research has a new director-general, according to ScienceInsider.

A new study links more than a hundred genes to autism spectrum disorder, Discover's D-brief blog reports.

In Science this week: genetic mutations typically associated with esophageal cancer are common in older, healthy individuals, and more.