This Week in Cell

New York University School of Medicine's Evgeny Nudler et al. link RNA polymerase backtracking to genome instability in E. coli in Cell this week. In its paper, the NYU team shows that "co-directional collisions between backtracked RNAP [RNA polymerase] and replisome lead to DSBs [double-strand breaks]" in the bacterium. It also shows that "active ribosomes preserve genome integrity" by preventing such backtracking.

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.