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New York University School of Medicine's Evgeny Nudler et al. link RNA polymerase backtracking to genome instability in E. coli in Cell this week. In its paper, the NYU team shows that "co-directional collisions between backtracked RNAP [RNA polymerase] and replisome lead to DSBs [double-strand breaks]" in the bacterium. It also shows that "active ribosomes preserve genome integrity" by preventing such backtracking.

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AstraZeneca has released its coronavirus vaccine trial protocol, according to the New York Times.

Time magazine looks into how liquid biopsies are changing cancer care.

According to the Guardian, more than 150 countries have signed on to a global SARS-CoV-2 vaccine plan.

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