This Week in Cell

In Cell Metabolism this week, researchers at the University of Iowa report two mRNA signatures of skeletal muscle atrophy — 63 mRNAs regulated by fasting in both human and mouse muscle, and 29 mRNAs regulated by both fasting and spinal cord injury in human muscle — which they applied to query the Broad Institute's Connectivity Map.

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23andMe's Anne Wojcicki ponders DNA and what it means to be human in a New York Times essay.

A new estimate places the last universal common ancestor to life on Earth as living 3.9 billion years ago, Inverse reports.

In PNAS this week: retinitis pigmentosa gene therapy, role of microbiome in growth stunting, and more.

Bloomberg reports that researchers and drug companies are modeling anti-obesity treatments after the rare genetic condition essential fructosuria.