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In the Water

NDM-1, a gene that confers antibiotic resistance in bacteria, is in the water supply of New Delhi, reports The Guardian. Using PCR and sequencing, Cardiff University researchers found the gene in 51 of the 171 samples of seepage and two of the 50 drinking water samples from New Delhi, but not in the wastewater or drinking water samples from Cardiff, as they report in The Lancet Infectious Disease. The bacteria found with the resistance gene include those that cause dysentery and cholera. "There are now superbugs that do not respond to any drug. Given the growth of travel and trade in Europe and across the world, people should be aware that until all countries tackle this, no country alone can be safe," says Zsuzsanna Jakab, WHO regional director for Europe, in The Guardian.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.