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Watch Out for the Falling Axe

In the latest round of job cuts in the pharma sector, Bristol-Myers Squibb announced it will be cutting 10 percent more of its 37,000-person workforce (they had a 10 percent reduction last year), according to the Wall Street Journal's Health Blog. "Add in weak pipelines of new drugs, tough regulatory scrutiny, and pricing pressure from big purchasers, and it's clear why the industry is seeing round after round of job cut," Jacob Goldstein adds.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.