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The Vulnerabilities

By exploiting genetic vulnerabilities, genome editing may be able to help combat disease, the Boston Herald's Jordan Graham says. For instance, Graham notes that the HIV virus cannot infect some people who lack a specific protein, and genome editing could be used in others so that they do not produce that protein and thus cannot be infected.

"We take out cells, correct it, ... and put the cell back into the person," says the Broad Institute's Feng Zhang, who developed the CRISPR approach. "It's a biotechnology that allows us to go into the genome, the DNA of a cell, and make very exact changes within the DNA."

However, it would be a time-consuming process to do that for HIV, Graham adds, as every blood cell in the person would have to be removed and changed.

Still, Zhang says that the process could address other diseases like sickle cell anemia and most viruses.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.