Case Western and UNC researchers used phage display and molecular modeling to identify a binding ligand with high affinity for CRIP1, or cysteine-rich intestinal protein 1, which is a novel biomarker for early detection of breast cancer. After modelling and synthesizing a new peptide, A1M, they found that A1M had a 10 to 28-fold improvement in binding affinity than the original sequence motifs from the phage display work.

To read the full story....

Register for Free.

...and receive Daily News bulletins.

Already have an account?
Login Now.

Science speaks with the University of Michigan's Jedidiah Carlson, who has tracked population genetic discussions at white nationalist sites.

Gene therapies could qualify for a faster US Food and Drug Administration approval process, according to Stat News.

NPR reports that the US House of Representatives has passed a bill to enable terminally ill patients access to experimental drugs.

In Genome Research this week: inversion variants mapped in human, non-human primate genomes; transcriptome profiling of maize, sorghum; and more.