Up, Up, Up

It's no secret that pharmaceutical companies are having problems filling their pipelines, says Pharmalot's Ed Silverman. On top of slashing R&D budgets, many companies are now finding that the cost of clinical trials is on the rise, across all phases. "There is increasing competition for trial sites and clinical research organizations that can yield reliable, high quality data," Silverman says.

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Germany's Project DEAL has come to an agreement with the publisher Wiley over journal access and open-access publishing, ScienceInsider reports.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

A Canadian panel recommends public coverage of the gene therapy Kymriah if its cost comes down, the Globe and Mail reports.

In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.