Under Control

At Bitesize Bio, Shoba Anantha discusses how UNG can be useful in PCR analysis. Amplicons generated during PCR have dUTPs incorporated in them, Anantha notes, and UDG, the enzyme encoded in UNG, targets those dUTPs. If those amplicons are a source of contamination, using UDG before any other PCR reaction will target and make those sites abasic so that they will not "serve as good templates for Taq polymerase" while the original template will remain untouched.

To read the full story....

Register for Free.

...and receive Daily News bulletins.

Already have a GenomeWeb or 360Dx account?
Login Now.

NPR reports that with medical data being big business, some companies want to get patients involved.

The Asbury Park Press reports on the startup Genomic Prediction's test to determine an embryo's risk of disease.

In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.

Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.