Uncle Sam's Science

The US Department of Defense has become one of the biggest funders of synthetic biology research through the Defense Advanced Research Projects Agency, which is funding projects that use biology to produce new materials, fuels, and medicines, says Nature's Erica Check Hayden at Discover magazine's The Crux blog.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.