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It's Ultra

Researchers at the University of Connecticut have developed a new method of multiple reaction monitoring mass-spec that can quantify targeted proteins. The team, led by Xudong Yao, calls it ultrathroughput MRM mass-spec. "It integrates the use of stable isotope dilution-multiple reaction monitoring mass spectrometry and peptide derivatization with inexpensive and commercial chemicals," the researchers write in their Analytical Chemistry study. Yao and his team say UMRM technology will have a "broad impact" on basic and applied biological and biomedical research. "Because of the flexibility in experimental design and reagent selection and the applicability of commercially available mass spectrometers, immediate adoption of the UMRM technology for targeted protein quantitation is expected," they write.

The Scan

Missed Early Cases

A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports.

Limited Journal Editor Diversity

A survey finds low diversity among scientific and medical journal editors, according to The Scientist.

How Much of a Threat?

Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned.

PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs

In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.