Twin-Sanity!

"Twin studies are pretty much useless," says Slate's Brian Palmer. The idea of using twins to track heritability is an old one, but critics say the idea is worn out and can lead to potentially ambiguous conclusions about how genes are inherited and how they affect a person compared to the person's environment. Despite numerous indications that conclusions drawn from twin studies are "deeply flawed," researchers continue to do these studies and write papers based on the results, Palmer says.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.