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It's the time of year for lists and navel-gazing. Science named the first quantum machine as the breakthrough of the year. The runners-up, though, included synthetic genomes, the sequencing of the Neandertal genome, next-gen genomics, and exome sequencing, showing that the 'omics fields have a bit to offer.

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The US Patent and Trademark Office is opening another interference proceeding in the CRISPR patent fight.

There's increasing genetic evidence that a number of ancient hominins may have contributed to the human gene pool, according to Discover's The Crux blog.

The Japan News writes that Japan needs to seize the opportunity to ensure that a wide number of people benefit from personalized cancer treatments.

In Cell this week: messenger RNA expression and translation, RNA localization atlas, and more.