The authors of a highly cited Science paper from 2004 on the synthesis of glycoproteins have retracted it, reports The Scientist. As the authors note in their retraction, "the lab notebooks are no longer available to replicate the original experimental conditions, and we are unable to introduce this amino acid into myoglobin with the information and reagents currently in hand." Senior author Peter Schultz tells The Scientist that his lab plans to continue to study the glycosylation of amino acids. "There are clearly complexities associated with suppression and cellular bioavailablity of these and other glycosylated amino acids that we did/do not understand," Schultz wrote in an email.
Dec 02, 2009