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True for E. coli, True for an Elephant?

Michael White blogs at Adaptive Complexity about looking at genomes from a network or mathematical approach. "Inferring network connections from genomic data may be great for putting together the wiring diagrams, but without directed experimentation on a given system, we can't say much about how a system is carrying out its function," he writes. "The biggest implication of this idea that there is no automatic or prescribed way of finding important functional features of systems is that our ability to generalize in systems biology may be limited."

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.