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The Trial and Error Part is Depressing Enough

Researchers at Munich's Max Planck Institute for Psychiatry showed that mutations in the ABCB-1 gene affect how three widely used antidepressants work – or don't work, reports this Reuters article. Using mice genetically engineered to lack this gene, they found the gene and the protein blocked Celexa and Effexor but not Remeron. Since 30 percent of people don't respond to antidepressants, this could be the first step toward a pharmacogenomic test for efficacy.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.