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Tough Times for GWAS

Here's a post from the Annals of Neurology blog reacting to the problems that arose as scientists realized they could identify individuals even from seemingly "anonymized" pooled DNA samples. This threatens to halt advances from genome-wide associations studies, writes Brenda Patoine, "just as the power of these studies to detect risk-conferring alleles in complex genetic diseases is being realized." She notes that the NIH decision to close access to its GWAS databases has had "ripple effects throughout the genetics research community, as universities mull whether to pull data from their own Web sites and grapple with issues of informed consent in the face of the apparent vulnerabilities to participant confidentiality."

 

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.