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Tools for the Mac Users Club

There are a variety of reasons that people buy Macs, and Bitesize Bio's Nick Oswald adds one more for bioresearchers: a company called Mekentosj develops software for bioscientists and much of it is freely available, though it's all for Macs. One freeware tool that Oswald recommends is 4 peaks, which he says is "a very slick, robust and easy-to-use DNA sequence viewer." Another is Target Scanner, "an easy-to-use graphical interface for identifying microRNA target genes." The company also offers a literature organizer, called Papers, for $42 as well as iPhone apps.

The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.