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A Tiresome Debate

Derek Lowe of In the Pipeline blogs about another recent paper that reports no connection between the xenotropic murine leukemia virus-related virus and patients surveyed with chronic fatigue syndrome. Harriet Groom et al. write that, in the examination of 170 samples from CFS patients from two cohorts and 395 controls for XMRV infection, they “have not identified XMRV DNA in any samples by PCR.” These results are among several others that contradict the findings reported in an October 2009 Science paper, which suggest that the retrovirus is detected in the blood cells of patients with CFS.

The Scan

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.

Study Highlights Pitfall of Large Gene Panels in Clinical Genomic Analysis

An analysis in Genetics in Medicine finds that as gene panels get larger, there is an increased chance of uncovering benign candidate variants.

Single-Cell Atlas of Drosophila Embryogenesis

A new paper in Science presents a single-cell atlas of fruit fly embryonic development over time.

Phage Cocktail Holds Promise for IBD

Researchers uncovered a combination phage therapy that targets Klebsiella pneumonia strains among individuals experiencing inflammatory bowel disease flare ups, as they report in Cell.