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By the Time They're Done Analyzing, There Won't Be Any Genes Left

Poor Steve Salzberg. Not only does GTO routinely misspell his name, but now he's 4,000 genes short of where he was a couple of weeks ago.

In research he calls "compelling," Michele Clamp and cronies from the Broad Institute have published work in PNAS saying that the total number of genes in the human genome should be reduced from previous estimates of about 25,000 to 20,500. "Their analysis is pretty convincing - they did careful alignments of all human genes to both mouse and dog, and were able to identify several thousand genes that didn't seem to exist in our furry friends," Salzberg writes.


The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.