Launching an independent research career can be tough, especially during challenging budget times. At the Rock Talk Blog, Sally Rockey, the deputy director for extramural research at the US National Institutes of Health, notes that the average age for new investigators — researchers who haven't received a major independent research award — is 42 for PhDs and 44 for MDs or MD/PhDs.

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In Science this week: factors influencing retrotransposon integration sites, and more.

A bioethicist argues for the responsible use of germline gene editing.

Some breweries are using DNA-based testing to determine whether unwanted bacteria are affecting their beers, The Verge reports.

Standardized N-of-1 trials will be needed to test out personalized medicines, writes Nicholas Schork from the J. Craig Venter Institute at Nature.