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Three Times the Charm?

A May 2010 Nature paper from the University of Chicago's Lina Chen and colleagues that reported that CD95 works to promote tumor growth has now been corrected three times, according to Ivan Oransky at Retraction Watch.

The first correction, issued online in March 2011, noted that an experimental error due to antibody cross-reactions affected their western blot analysis and that, after fixing the error, the result from that aspect of the study was no longer statistically significant. The second correction amended the first correction, saying the first letter contained the wrong panels.

Last week's correction says that the original article also included an incorrect actin blot and that some western blog data, which had been included as supplementary data, "were either misinterpreted or raw data could not be located." The researchers write that they repeated the experiment and were able to confirm their prior results. "All the conclusions of the original Letter are intact except for the data for the original Fig. 4f and g on the phosphorylation level of c-Jun and JNK in the livers of CD95-deficient mice, which have been corrected in two previous Corrigenda," the authors write. They add that first author Chen declined to sign the corrigenda.

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.