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For Those 'Poor, Messed Up Gels'

Bitesize Bio has been talking about SDS-PAGE lately with a primer on how it works and tips on how to make it work better, but this time Nick discusses how they go wrong. He points to a guide and photo gallery that Rice University's David Caprette has pulled together, called the SDS-PAGE Hall of Shame. "By clicking on the picture that looks most like your poor, messed up gel you will be given a pearl of wisdom that suggests what you might have done wrong so you can remedy it in the future," Nick writes.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.