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For Those Pesky Last Five

There are a number of new tests entering the marketplace that recommend certain diets to users based on their genetic profiles. "The theory behind the (not inexpensive) offer is that different people are genetically inclined to process calories in different ways and are better off eating and working out using methods that sync with those predisposed metabolisms," reports Whole Living. The article, which appears in the December 2012 issue of the magazine, notes that there are a wide range of companies that offer such tests, from the credible to the not-so-credible.

In addition, the tests, it says, are based on associations and cannot say for sure whether a certain diet will lead an individual to lose weight. "But for people who've plateaued at 5 or 10 pounds over their target weight, tweaking their fats and carbs based on an admittedly imperfect genetic test could w ell provide a breakthrough. And even skeptics agree that the imprimatur of hard science can help people wrestle with the hardest part of a diet — staying on it," Whole Living adds.

The Scan

Y Chromosome Study Reveals Details on Timing of Human Settlement in Americas

A Y chromosome-based analysis suggests South America may have first been settled more than 18,000 years ago, according to a new PLOS One study.

New Insights Into TP53-Driven Cancer

Researchers examine in Nature how TP53 mutations arise and spark tumor development.

Mapping Single-Cell Genomic, Transcriptomic Landscapes of Colorectal Cancer

In Genome Medicine, researchers present a map of single-cell genomic and transcriptomic landscapes of primary and metastatic colorectal cancer.

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.