A post by blogger Coturnix at Blog Around the Clock discusses Jean-Claude Bradley's open notebook idea. Open notebook science is different than open access in that it allows the reader to see the processes unfold — including all the missteps that don't make it into the journal paper. Now that's scary.

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A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.