University of Washington researchers used a proteomics approach to characterize Drosophila seminal fluid that is transferred to the female fly. These proteins fill a variety of roles, such as aiding in sperm capacitation and fertilization. Using mass spectrometry, the researchers confirmed predicted seminal fluid proteins and identified new ones, including two new classes of proteins, and also estimated the relative abundance of the proteins. "Our experiments illustrate the power of combining proteomics with evolutionary biology to address fundamental questions about reproduction," the authors write.
There's a Proteome We Didn't Expect
Jul 29, 2008