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There's a Proteome We Didn't Expect

University of Washington researchers used a proteomics approach to characterize Drosophila seminal fluid that is transferred to the female fly. These proteins fill a variety of roles, such as aiding in sperm capacitation and fertilization. Using mass spectrometry, the researchers confirmed predicted seminal fluid proteins and identified new ones, including two new classes of proteins, and also estimated the relative abundance of the proteins. "Our experiments illustrate the power of combining proteomics with evolutionary biology to address fundamental questions about reproduction," the authors write.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.