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Making RNAi work in therapeutic application is tricky, and here, Derek Lowe reports on a paper published in Nature last week that does a good job demonstrating just how much researchers don't know. They used RNAi to knock down VEGF, whose overactivation leads to macular degeneration.

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In a letter, about two dozen researchers criticize the World Health Organization investigation into the origins of SARS-CoV-2 and call for a new inquiry, the Wall Street Journal reports.

National Geographic reports that nine great apes at the San Diego Zoo have been vaccinated against SARS-CoV-2.

Janet Woodcock, the acting commissioner of the US Food and Drug Administration, speaks with NPR about SARS-CoV-2 testing and vaccines in the US.

In Science this week: genetic study of kidney fibrosis implicates the SOX9-NAV3-YAP1 axis.