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That's Probably More Than You Wanted to Know About Your Liver

May 07, 2008

In work published today in PLoS Biology, researchers led by Eric Schadt at Merck have performed a genome-wide association study of gene expression in the human liver, validating a number of genes involved in diseases linked to malfunction of this organ. They profiled more than 39,000 transcripts and genotyped 782,476 SNPs in over 400 human liver samples, finding more than 6,000 associations between SNP genotypes and liver gene expression traits.

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