With personal genomics hitting the big time, Thomas Mailund wonders about the impact that risk assessments will have on consumer behavior -- and concludes that it will be nominal. Increases in risk of developing a disease such as cancer due to genetics is often small, from 0.1 percent to 0.15 percent, says Mailund. The risk associated with smoking and cancer is much larger, he adds, and that doesn't affect people's behavior, so why would genetics?

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.