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The Technology Pilot

If you've been wondering how the 1,000 Genomes Project is doing, here's an account from Dan Koboldt at his MassGenomics blog about last week's meeting at Baylor where participants discussed the "Pilot 3" phase of the project. "Unlike pilots 1 and 2, which emphasized whole genome sequencing to low or high coverage, respectively, in Pilot 3, the exons of 1,000 genes (~1.5 Mbp total) were selectively targeted for sequencing by capture technologies," Koboldt writes. The team is also checking data across platforms and pipelines. "Overall, the Pilot 3 variant calls are looking good - dbSNP concordances in the 70-80% range or higher, and transition/transversion ratios of about 3-3.50 - and consistent across 454 and Solexa data from multiple centers," he writes.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.