Discovering Biology in a Digital World's Sandra Porter says the coolest thing to do with next-gen sequencing is to look at transcriptomes. If you are new to dealing with next-gen sequencing data, take a look at her post to see how she handles sequence data from NCBI, aligning the reads, and comparing the different mouse and human isoforms of a gene of interest.

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The US National Institutes of Health has developed guidelines to gauge whether frail chimpanzees are healthy enough to be moved to a retirement sanctuary.

Osamu Shimomura, who won the 2008 Nobel Prize in Chemistry for his work on green fluorescent protein, has died.

In PLOS this week: analytical approach for finding new genetic associations, analysis of Streptococcus pyogenes-infecting viruses, and more.

Stat News reports that the head of IBM Watson Health is leaving her post.