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Taking Stock of Gates

It's been five years since the Bill and Melinda Gates Foundation began giving out grants for researchers to study global health issues and this article in The New York Times examines the results thus far. "We were naïve when we began," Bill Gates tells the Times. However, he adds that "on attention to ways that lives might be saved through scientific advances, I'd give us an A." The Times goes through a few of the Gates initiatives, such as work toward finding thermostable vaccines, developing rapid, point-of-care diagnostic tests, and adding vitamins and nutrients to African crops. It's a mixed report card: some researchers met their goals, others attracted commercial backing and yet others won't have their grants renewed because of seemingly insurmountable obstacles, though others are trucking onward. "Without Gates, we wouldn't have been able to put together the team we did," says Rafi Ahmed, an Emory University immunologist who studies T-cells. "The money, and the fantastic vision of a grand challenge — that's been one of the best things."

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.