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A paper published this week in PNAS from scientists at the Broad Institute looks at how to better identify the proteins to which small molecules and drugs bind to effect their mechanism of action. The group used a combination of quantitative proteomics, or SILAC, and affinity enrichment to find these proteins in an "unbiased, robust and comprehensive" way. Particularly, they detail applying the method to identifying targets of kinase inhibitors and immunophilin binders.

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Newsweek discusses the privacy issues raised by digital medicine.

A group of statisticians wants to eliminate researchers' reliance on 'statistical significance,' according to NPR.

In Nature this week: genetic analysis of Anatolian farmers, cotton genome analysis, and more.

Matt Hancock, the UK health secretary, is calling for the swift rollout of predictive genetic tests, the Guardian reports.

Mar
27
Sponsored by
Swift Biosciences

Sequencing workflows require library quantification and normalization to ensure data quality and reduce cost. 

Apr
17
Sponsored by
Isoplexis

This webinar will provide an overview of current biomarker strategies for guiding the use of combination checkpoint immunotherapies in blood cancers.

Apr
30
Sponsored by
Lexogen

This webinar will discuss novel long-read transcript sequencing (LRTseq) methods for transcriptome annotation that could increase the efficiency and accuracy of future sequencing projects.