A group of German researchers led by Pawel Smialowski and Philipp Pagel created a database, called the Negatome, of protein interactions that are unlikely to occur. As the report in Nucleic Acids Research, they scoured the literature for evidence against physical interactions of proteins and also analyzed protein complexes deposited in the Protein Data Bank to come up with their database, which may be found here.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.