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A new study in Cancer Research from Loyola University Chicago Stritch School of Medicine researchers is providing new clues as to how estrogen fuels many breast cancers. The researchers have found that the hormone inhibits the MLK3 protein that causes normal cell death. When the protein is blocked, cancer cells can grow uncontrolled, and can be resistant to chemotherapy.

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The UK and the European Union have come to a sticking point in the negotiation of how the UK might remain involved in the Horizon Europe research program, the Guardian reports.

The New York Times reports that experts pushed during a meeting of an FDA advisory board for the agency to require more safety data from SARS-CoV-2 vaccine trials.

The Washington Post reports Moderna expects that it will have enough data on its candidate SARS-CoV-2 vaccine to submit to regulatory authorities by mid-November.

In Science this week: ANXA11 variants affect calcium homeostasis and stress granule disassembly in ALS, and more.