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Still Looking for a Head

Wall Street Journal reports that Peggy Hamburg and Joshua Sharfstein are expected to become commissioner and deputy commissioner, respectively, of the US Food and Drug Administration. Hamburg was a health commissioner in New York City, and Sharfstein is the health chief in Baltimore. "The White House wants to position the FDA commissioner as someone who will lead the agency back to its core mission of public health, and the focus on Dr. Hamburg and Dr. Sharfstein fits that message, said people close to the situation," the article says.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.